Supply high purity medical intermediate and reagent
2017年11月14日星期二
Dextroamphetamine whastapp;8618031153937 ada@tuskwei.com sky;18031153937@189.cn
Dextroamphetamine
INN
:
Dexamfetamine
Clinical data
Trade names
Dexedrine, Metamina, Attentin, Zenzedi, Procentra, Amfexa
Synonyms
D
-Amphetamine
AHFS
/
Drugs.com
Monograph
MedlinePlus
a605027
License data
US
FDA
:
Dextroamphetamine
Pregnancy
category
AU
:
B3
US
:
C
(Risk not ruled out)
Dependence
liability
Physical
: None
Psychological
: Moderate
[1]
[2]
Addiction
liability
Moderate
Routes of
administration
oral
ATC code
N06BA02
(
WHO
)
Legal status
Legal status
AU
:
S8
(Controlled)
CA
:
Schedule I
DE
:
Anlage III
(Special prescription form required)
UK
:
Class B
US
:
Schedule II
Pharmacokinetic
data
Bioavailability
Oral 75–100%
[6]
Protein binding
15–40%
[7]
Metabolism
CYP2D6
,
[3]
DBH
,
[4]
FMO3
[5]
Onset of action
IR
dosing: 0.5-1.5 hours
[8]
[9]
XR
dosing: 1.5–2 hours
[10]
[11]
Biological half-life
9–11 hours
[3]
[12]
pH
-dependent: 7–34 hours
[13]
Duration of action
IR
dosing: 3–6 hours
[10]
[14]
XR
dosing: 8–12 hours
[2]
[10]
[14]
Excretion
Renal (45%);
[15]
urinary pH-dependent
Identifiers
IUPAC name
[show]
CAS Number
51-64-9
PubChem
CID
5826
IUPHAR/BPS
2147
DrugBank
DB01576
ChemSpider
5621
UNII
TZ47U051FI
KEGG
D03740
ChEBI
CHEBI:4469
ChEMBL
CHEMBL612
ECHA InfoCard
100.000.103
Chemical and physical data
Formula
C
9
H
13
N
Molar mass
135.20622
3D model (
JSmol
)
Interactive image
Density
0.913 g/cm
3
Boiling point
201.5 °C (394.7 °F)
Solubility in water
20 mg/mL (20 °C)
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