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INN: Dexamfetamine

Clinical data
Trade names	Dexedrine, Metamina, Attentin, Zenzedi, Procentra, Amfexa
Synonyms	D-Amphetamine
AHFS/Drugs.com	Monograph
MedlinePlus	a605027
License data	US FDA: Dextroamphetamine
Pregnancy category	AU: B3 US: C (Risk not ruled out)
Dependence liability	Physical: None Psychological: Moderate[1][2]
Addiction liability	Moderate
Routes of administration	oral
ATC code	N06BA02 (WHO)
Legal status
Legal status	AU: S8 (Controlled) CA: Schedule I DE: Anlage III (Special prescription form required) UK: Class B US: Schedule II
Pharmacokinetic data
Bioavailability	Oral 75–100%[6]
Protein binding	15–40%[7]
Metabolism	CYP2D6,[3] DBH,[4] FMO3[5]
Onset of action	IR dosing: 0.5-1.5 hours[8][9] XR dosing: 1.5–2 hours[10][11]
Biological half-life	9–11 hours[3][12] pH-dependent: 7–34 hours[13]
Duration of action	IR dosing: 3–6 hours[10][14] XR dosing: 8–12 hours[2][10][14]
Excretion	Renal (45%);[15] urinary pH-dependent
Identifiers
IUPAC name[show]
CAS Number	51-64-9
PubChem CID	5826
IUPHAR/BPS	2147
DrugBank	DB01576
ChemSpider	5621
UNII	TZ47U051FI
KEGG	D03740
ChEBI	CHEBI:4469
ChEMBL	CHEMBL612
ECHA InfoCard	100.000.103
Chemical and physical data
Formula	C9H13N
Molar mass	135.20622
3D model (JSmol)	Interactive image
Density	0.913 g/cm3
Boiling point	201.5 °C (394.7 °F)
Solubility in water	20 mg/mL (20 °C)

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